Basic Information
ID: ALA4667413
Type: Binding
Description: Inverse agonist activity at RORgamma in human CD4+ T cells assessed as inhibition of IL17A secretion after 72 hrs by ELISA
Organism: Homo sapiens
Cell type: CD4+ve Th
Activity Charts
Bioactivity
Activity Types for Assay ALA4667413
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.37 | 4.21 | 4.21 |
| 588.52 | 4.73 | 4.73 |
| 562.40 | 5.09 | 5.09 |
| 616.57 | 5.54 | 5.54 |
| 574.49 | 4.51 | 4.51 |
| 519.37 | 6.23 | 6.23 |
| 602.54 | 5.33 | 5.33 |
| 604.48 | 6.16 | 6.16 |
| 549.40 | 5.59 | 5.59 |
| 533.40 | 6.62 | 6.62 |
| 613.57 | 6.21 | 6.21 |
| 584.53 | 6.00 | 6.00 |
| 642.61 | 6.72 | 6.72 |
| 576.42 | 5.35 | 5.35 |
| 585.51 | 5.39 | 5.39 |
| 590.45 | 5.60 | 5.60 |
| 585.51 | 5.39 | 5.39 |
| 507.53 | 4.04 | 4.04 |
| 563.42 | 6.25 | 6.25 |
| 628.46 | 5.22 | 5.22 |
| 563.43 | 6.25 | 6.25 |