Basic Information
ID: ALA4667418
Type: Functional
Description: Invivo inverse agonist activity at RORgamma in MOG(35-55) peptide/PTX-induced mechanistic C57BL/6 mouse model assessed as anti-CD3 induced TNFalpha level in serum at 10 mg/kg, po dosed for 5 days during MOG/PTX priming and followed by 45 mins prior to anti-CD3 challenge and measured after 2 hrs relative to control
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4667418
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.57 | 5.54 | 5.54 |