Basic Information
ID: ALA4667427
Type: Functional
Description: Positive allosteric modulation of human M4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay relative to acetylcholine
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4667427
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.41 | 2.48 | 2.48 |
| 415.91 | 2.52 | 2.52 |
| 483.48 | 2.03 | 2.03 |
| 400.86 | 1.52 | 1.52 |
| 340.41 | 2.18 | 2.18 |
| 438.34 | 2.91 | 2.91 |
| 324.41 | 2.48 | 2.48 |
| 437.45 | 2.57 | 2.57 |
| 439.42 | 1.50 | 1.50 |
| 428.95 | 3.43 | 3.43 |
| 410.29 | 2.30 | 2.30 |
| 477.30 | 3.92 | 3.92 |
| 354.44 | 2.49 | 2.49 |
| 459.40 | 2.95 | 2.95 |
| 443.84 | 2.66 | 2.66 |
| 421.91 | 2.44 | 2.44 |
| 374.86 | 2.25 | 2.25 |
| 358.85 | 3.13 | 3.13 |
| 425.40 | 1.71 | 1.71 |
| 338.44 | 2.79 | 2.79 |
| 451.48 | 3.13 | 3.13 |
| 427.29 | 3.04 | 3.04 |
| 443.75 | 3.56 | 3.56 |
| 439.42 | 2.02 | 2.02 |
| 423.42 | 2.32 | 2.32 |
| 439.33 | 2.91 | 2.91 |