ID: ALA4667925
Type: Unassigned
Description: Ratio of IC50 for antimalarial activity against CQ-sensitive Plasmodium falciparum 3D7 incubated for 72 hrs by SYBR Green-1 dye based fluorescence assay to Plasma concentration in NIH mouse infected with Plasmodium chabaudi ASS at 10 mg/kg, po qd for 4 days starting from 4 hrs post-parasite inoculation and measured at 24 hrs post-dosing on day 4 by LC/MS analysis
Format: BAO_0000218
Target: Unchecked(ALA612545)
Document: ALA4665665
Ratio of IC50 for antimalarial activity against CQ-sensitive Plasmodium falciparum 3D7 incubated for 72 hrs by SYBR Green-1 dye based fluorescence assay to Plasma concentration in NIH mouse infected with Plasmodium chabaudi ASS at 10 mg/kg, po qd for 4 days starting from 4 hrs post-parasite inoculation and measured at 24 hrs post-dosing on day 4 by LC/MS analysis: 1
Bioactivity
Activity Types for Assay ALA4667925
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
391.44 | 3.19 | 3.19 |
449.49 | 4.82 | 4.82 |
387.47 | 3.28 | 3.28 |