Basic Information
ID: ALA4667947
Type: ADME
Description: Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cells using midazolam as substrate incubated for 30 mins in presence of NADPH-regenerating system by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4665665
Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cells using midazolam as substrate incubated for 30 mins in presence of NADPH-regenerating system by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4667947
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.44 | 3.19 | 3.19 |
| 449.49 | 4.82 | 4.82 |
| 387.47 | 3.28 | 3.28 |