Basic Information
ID: ALA4667958
Type: Binding
Description: Inhibition of recombinant Trypanosoma cruzi cruzain at 5 uM using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins without preincubation by fluorimetric analysis relative to control
Organism: Trypanosoma cruzi
Activity Charts
Bioactivity
Activity Types for Assay ALA4667958
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.18 | 4.12 | 4.12 |
| 245.28 | 2.68 | 2.68 |
| 267.36 | 4.26 | 4.26 |
| 270.33 | 4.90 | 4.90 |
| 361.23 | 4.16 | 4.16 |
| 338.28 | 4.62 | 4.62 |
| 332.36 | 4.70 | 4.70 |
| 367.28 | 3.70 | 3.70 |
| 510.43 | 7.68 | 7.68 |
| 571.68 | 7.18 | 7.18 |
| 456.98 | 5.34 | 5.34 |
| 397.54 | 3.75 | 3.75 |
| 438.90 | 4.04 | 4.04 |
| 395.89 | 3.28 | 3.28 |
| 403.92 | 4.79 | 4.79 |
| 487.77 | 6.43 | 6.43 |
| 430.52 | 5.53 | 5.53 |
| 422.44 | 5.33 | 5.33 |
| 341.72 | 4.16 | 4.16 |
| 726.97 | 5.87 | 5.87 |
| 447.54 | 6.42 | 6.42 |
| 494.66 | 4.96 | 4.96 |
| 329.38 | 2.38 | 2.38 |
| 340.79 | 4.72 | 4.72 |
| 357.41 | 4.88 | 4.88 |
| 373.41 | 4.50 | 4.50 |
| 479.54 | 3.31 | 3.31 |
| 228.34 | 3.17 | 3.17 |
| 453.33 | 5.78 | 5.78 |
| 423.43 | 3.39 | 3.39 |
| 460.54 | 6.38 | 6.38 |
| 326.40 | 4.99 | 4.99 |
| 554.51 | 7.90 | 7.90 |
| 268.14 | 4.11 | 4.11 |
| 345.83 | 2.90 | 2.90 |
| 334.38 | 3.52 | 3.52 |
| 394.43 | 3.54 | 3.54 |
| 358.39 | 3.93 | 3.93 |
| 463.96 | 4.65 | 4.65 |
| 420.56 | 6.03 | 6.03 |
| 362.44 | 4.50 | 4.50 |
| 268.36 | 3.67 | 3.67 |
| 382.25 | 5.79 | 5.79 |
| 274.32 | 2.76 | 2.76 |
| 524.58 | 7.52 | 7.52 |
| 362.27 | 3.63 | 3.63 |
| 501.37 | 7.04 | 7.04 |
| 434.56 | 5.33 | 5.33 |
| 462.62 | 5.40 | 5.40 |
| 432.91 | 5.43 | 5.43 |
| 293.32 | 3.76 | 3.76 |
| 425.96 | 4.84 | 4.84 |
| 281.14 | 4.29 | 4.29 |
| 400.46 | 4.42 | 4.42 |
| 315.84 | 4.99 | 4.99 |
| 425.96 | 4.84 | 4.84 |
| 278.36 | 4.55 | 4.55 |
| 343.90 | 4.82 | 4.82 |
| 608.74 | 6.86 | 6.86 |
| 367.49 | 3.86 | 3.86 |
| 440.55 | 4.76 | 4.76 |
| 363.89 | 4.35 | 4.35 |
| 310.38 | 3.59 | 3.59 |
| 489.52 | 5.36 | 5.36 |
| 472.45 | 5.30 | 5.30 |
| 493.57 | 5.11 | 5.11 |
| 313.36 | 2.81 | 2.81 |
| 592.66 | 8.85 | 8.85 |
| 431.56 | 6.92 | 6.92 |
| 456.64 | 4.45 | 4.45 |