Basic Information
ID: ALA4667969
Type: Binding
Description: Inhibition of recombinant Trypanosoma cruzi cruzain at 10 uM using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured at 12 sec interval for 5 mins by fluorimetric analysis relative to control
Format: BAO_0000357
Organism: Trypanosoma cruzi
Target: Cruzipain(ALA3563)
Document: ALA4665666
Inhibition of recombinant Trypanosoma cruzi cruzain at 10 uM using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured at 12 sec interval for 5 mins by fluorimetric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4667969
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.33 | 4.90 | 4.90 |
| 367.28 | 3.70 | 3.70 |
| 438.90 | 4.04 | 4.04 |
| 395.89 | 3.28 | 3.28 |
| 403.92 | 4.79 | 4.79 |
| 341.72 | 4.16 | 4.16 |
| 357.41 | 4.88 | 4.88 |
| 326.40 | 4.99 | 4.99 |
| 268.14 | 4.11 | 4.11 |
| 362.44 | 4.50 | 4.50 |
| 293.32 | 3.76 | 3.76 |
| 400.46 | 4.42 | 4.42 |
| 489.52 | 5.36 | 5.36 |
| 456.64 | 4.45 | 4.45 |