Basic Information
ID: ALA4668049
Type: Binding
Description: Selectivity index, ratio of IC50 for human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method to IC50 for human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method
Format: BAO_0000019
Organism: Homo sapiens
Target: Cholinesterases; ACHE & BCHE(ALA2095233)
Document: ALA4665668
Selectivity index, ratio of IC50 for human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method to IC50 for human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4668049
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 250.34 | 2.76 | 2.76 |
| 343.82 | 2.60 | 2.60 |
| 309.37 | 1.95 | 1.95 |
| 367.41 | 2.48 | 2.48 |
| 354.37 | 1.86 | 1.86 |
| 397.44 | 2.48 | 2.48 |
| 323.36 | 2.16 | 2.16 |
| 307.36 | 2.46 | 2.46 |
| 388.27 | 2.71 | 2.71 |
| 377.37 | 2.97 | 2.97 |
| 352.35 | 2.37 | 2.37 |
| 341.80 | 3.11 | 3.11 |
| 341.37 | 1.36 | 1.36 |
| 343.34 | 2.74 | 2.74 |
| 339.36 | 1.87 | 1.87 |
| 325.35 | 2.60 | 2.60 |
| 345.35 | 2.23 | 2.23 |
| 375.35 | 3.48 | 3.48 |
| 386.25 | 3.22 | 3.22 |
| 393.37 | 2.85 | 2.85 |
| 323.36 | 2.16 | 2.16 |
| 327.36 | 2.09 | 2.09 |
| 325.37 | 1.65 | 1.65 |
| 391.35 | 3.36 | 3.36 |
| 399.45 | 1.97 | 1.97 |