Basic Information
ID: ALA4668050
Type: Binding
Description: Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Beta-secretase 1(ALA4822)
Document: ALA4665668
Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4668050
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 343.82 | 2.60 | 2.60 |
| 321.38 | 2.77 | 2.77 |
| 309.37 | 1.95 | 1.95 |
| 367.41 | 2.48 | 2.48 |
| 354.37 | 1.86 | 1.86 |
| 397.44 | 2.48 | 2.48 |
| 323.36 | 2.16 | 2.16 |
| 307.36 | 2.46 | 2.46 |
| 388.27 | 2.71 | 2.71 |
| 377.37 | 2.97 | 2.97 |
| 321.38 | 2.77 | 2.77 |
| 352.35 | 2.37 | 2.37 |
| 341.80 | 3.11 | 3.11 |
| 341.37 | 1.36 | 1.36 |
| 325.37 | 1.65 | 1.65 |
| 343.34 | 2.74 | 2.74 |
| 339.36 | 1.87 | 1.87 |
| 325.35 | 2.60 | 2.60 |
| 323.40 | 2.26 | 2.26 |
| 345.35 | 2.23 | 2.23 |
| 375.35 | 3.48 | 3.48 |
| 386.25 | 3.22 | 3.22 |
| 393.37 | 2.85 | 2.85 |
| 323.36 | 2.16 | 2.16 |
| 327.36 | 2.09 | 2.09 |
| 325.37 | 1.65 | 1.65 |
| 391.35 | 3.36 | 3.36 |
| 369.43 | 1.96 | 1.96 |
| 323.40 | 2.26 | 2.26 |
| 399.45 | 1.97 | 1.97 |