Assay Report Card

Basic Information

ID: ALA4668460

Type: Binding

Description: Allosteric inhibition of SHP2 in human KYSE-520 cells assessed as reduction in DUSP6 level at 30 uM incubated for 2 hrs by Taqman qRT-PCR analysis relative to control

Organism: Homo sapiens

Cell type: KYSE-520 cell line

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
432.874.134.13
446.853.823.82
573.993.823.82