Basic Information
ID: ALA4668577
Type: Binding
Description: Inhibition of recombinant human CFD catalytic domain (G24 to A253 residues) expressed in Escherichia coli (Rosetta) using Z-Lys-thiobenzyl and 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorecein as substrate preincubated for 1 hr followed by substrate addition by spectrofluorimetric method
Format: BAO_0000019
Organism: Homo sapiens
Target: Complement factor D(ALA2176771)
Document: ALA4665679
Inhibition of recombinant human CFD catalytic domain (G24 to A253 residues) expressed in Escherichia coli (Rosetta) using Z-Lys-thiobenzyl and 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorecein as substrate preincubated for 1 hr followed by substrate addition by spectrofluorimetric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4668577
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.56 | 5.08 | 5.08 |
| 465.43 | 3.68 | 3.68 |
| 431.54 | 3.88 | 3.88 |