Basic Information
ID: ALA4668599
Type: ADME
Description: Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4668599
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.55 | 4.37 | 4.37 |
| 494.01 | 3.64 | 3.64 |
| 531.44 | 4.21 | 4.21 |
| 581.07 | 6.14 | 6.14 |
| 670.86 | 3.09 | 3.09 |
| 356.45 | 3.16 | 3.16 |
| 357.44 | 2.49 | 2.49 |
| 470.02 | 3.55 | 3.55 |
| 608.69 | 4.17 | 4.17 |
| 1202.63 | ||
| 404.34 | 5.50 | 5.50 |
| 720.96 | 5.91 | 5.91 |
| 479.53 | 3.68 | 3.68 |
| 422.92 | 4.27 | 4.27 |
| 428.54 | 4.78 | 4.78 |