Basic Information
ID: ALA4668674
Type: Binding
Description: Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and nigerecin-induced IL-1beta production at 20 uM pre-stimulated with LPS for 5 hrs followed by compound treatment for 30 mins and then nigericin addition for 45 mins by ELISA
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA4668674
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 761.02 | 12.27 | 12.27 |
| 300.44 | 5.33 | 5.33 |
| 497.76 | 9.59 | 9.59 |
| 304.47 | 4.93 | 4.93 |