Basic Information
ID: ALA4668677
Type: Binding
Description: Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and nigericin-induced cleaved IL-1beta production at 20 uM pre-stimulated with LPS for 5 hrs before compound addition with ATP for 45 mins by Western blot analysis
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA4668677
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 761.02 | 12.27 | 12.27 |
| 497.76 | 9.59 | 9.59 |