Basic Information
ID: ALA4669201
Type: Binding
Description: Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis
Format: BAO_0000251
Organism: Bos taurus
Tissue: Retina
Subcellular Fraction: Microsome
Target: Retinoid isomerohydrolase(ALA4523306)
Document: ALA4665714
Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4669201
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.45 | 3.97 | 3.97 |
| 263.38 | 3.03 | 3.03 |
| 315.40 | 3.56 | 3.56 |