Assay Report Card

Basic Information

ID: ALA4669298

Type: Binding

Description: Inhibition of SPHK1/SPHK2 in human HL-60 cells assessed as induction of apoptosis by measuring spindle assembly checkpoint arrest at 20 uM after 16 hrs in presence of volasertib by Western blot analysis

Organism: Homo sapiens

Cell type: HL-60

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.924.894.89