Basic Information
ID: ALA4670194
Type: Binding
Description: Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at S473 residue incubated for 60 mins by alphalisa assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: PI3-kinase p110-gamma subunit(ALA3267)
Document: ALA4665778
Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at S473 residue incubated for 60 mins by alphalisa assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670194
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.49 | 4.14 | 4.14 |
| 495.51 | 4.46 | 4.46 |
| 563.58 | 6.24 | 6.24 |
| 414.47 | 2.83 | 2.83 |
| 412.50 | 3.86 | 3.86 |
| 548.57 | 6.66 | 6.66 |
| 417.51 | 4.05 | 4.05 |
| 481.56 | 4.34 | 4.34 |
| 469.55 | 3.82 | 3.82 |
| 451.53 | 4.71 | 4.71 |
| 413.49 | 3.43 | 3.43 |
| 388.47 | 4.25 | 4.25 |
| 347.42 | 3.04 | 3.04 |
| 479.47 | 4.21 | 4.21 |
| 412.50 | 3.86 | 3.86 |
| 347.42 | 3.04 | 3.04 |
| 424.51 | 4.10 | 4.10 |
| 419.49 | 3.04 | 3.04 |
| 427.51 | 3.44 | 3.44 |
| 468.54 | 2.02 | 2.02 |
| 495.51 | 4.46 | 4.46 |
| 481.56 | 4.71 | 4.71 |
| 346.43 | 3.87 | 3.87 |
| 347.42 | 3.04 | 3.04 |
| 389.46 | 3.42 | 3.42 |
| 468.54 | 2.48 | 2.48 |
| 428.50 | 4.00 | 4.00 |
| 481.48 | 4.15 | 4.15 |
| 427.51 | 3.44 | 3.44 |
| 425.50 | 3.50 | 3.50 |
| 389.46 | 3.42 | 3.42 |
| 443.43 | 4.13 | 4.13 |
| 487.56 | 2.94 | 2.94 |
| 389.46 | 3.42 | 3.42 |
| 403.49 | 3.81 | 3.81 |
| 389.46 | 3.42 | 3.42 |
| 425.51 | 2.83 | 2.83 |
| 347.42 | 3.04 | 3.04 |
| 457.54 | 2.90 | 2.90 |