Basic Information
ID: ALA4670198
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 1A2(ALA3356)
Document: ALA4665778
Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 to 20 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670198
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 548.57 | 6.66 | 6.66 |
| 427.51 | 3.44 | 3.44 |
| 481.48 | 4.15 | 4.15 |
| 443.43 | 4.13 | 4.13 |