Basic Information
ID: ALA4670358
Type: Functional
Description: Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293 cells assessed as inhibition of ghrelin-induced IP1 accumulation at 10^-5 M measured after 30 mins by IP1-d2 derivative based HTRF assay relative to ghrelin
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4670358
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 677.81 | 6.03 | 6.03 |
| 688.83 | 4.83 | 4.83 |
| 706.85 | 5.79 | 5.79 |
| 702.82 | 6.21 | 6.21 |
| 732.85 | 6.21 | 6.21 |
| 707.84 | 6.12 | 6.12 |
| 669.81 | 5.79 | 5.79 |
| 652.76 | 5.05 | 5.05 |
| 693.81 | 5.73 | 5.73 |
| 700.84 | 4.98 | 4.98 |
| 679.78 | 5.43 | 5.43 |
| 688.79 | 3.52 | 3.52 |
| 707.84 | 6.12 | 6.12 |
| 681.77 | 5.86 | 5.86 |
| 715.86 | 3.88 | 3.88 |
| 663.78 | 5.72 | 5.72 |