Basic Information
ID: ALA4670378
Type: Functional
Description: Inverse agonist activity at wild type human GHSR assessed as inhibition of ghrelin-induced BODIPY-FL GTPgammaS binding to Gq protein at 10 uM preincubated for 30 mins in presence of Galphaq and Gbeta1gamma2 followed by BODIPY-FL GTPgammaS addition and measured after 10 mins by lipid nanodisc-based fluorescence spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4670378
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 732.85 | 6.21 | 6.21 |
| 693.81 | 5.73 | 5.73 |
| 679.78 | 5.43 | 5.43 |
| 663.78 | 5.72 | 5.72 |