Basic Information
ID: ALA4670444
Type: Binding
Description: Inhibition of Clostridium botulinum BoNT/A intoxicated in hiPSC-derived neurons assessed as reduction in SNAP-25 cleavage using SNAP-25 as substrate treated 30 mins post toxin addition and measured 7 hrs post toxin addition by Western blot analysis
Organism: Clostridium botulinum
Cell type: Induced pluripotent stem cell-derived neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA4670444
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.39 | 4.48 | 4.48 |
| 471.43 | 3.34 | 3.34 |
| 443.37 | 2.56 | 2.56 |
| 485.45 | 3.73 | 3.73 |
| 412.36 | 4.09 | 4.09 |
| 457.40 | 2.95 | 2.95 |