Irreversible inhibition of Clostridium botulinum BoNT/A light chain expressed in Escherichia coli BL21 (DE3) assessed as ratio of Kinact/Ki using SNAP...

Basic Information

ID: ALA4670466

Type: Binding

Description: Irreversible inhibition of Clostridium botulinum BoNT/A light chain expressed in Escherichia coli BL21 (DE3) assessed as ratio of Kinact/Ki using SNAPtide as substrate preincubated with enzyme for 0.5 to 30 mins followed by substrate addition by Michaelis-Menten equation analysis

Format: BAO_0000019

Organism: Clostridium botulinum

Target:  Botulinum neurotoxin type A(ALA5192)

Document:  ALA4665791

Irreversible inhibition of Clostridium botulinum BoNT/A light chain expressed in Escherichia coli BL21 (DE3) assessed as ratio of Kinact/Ki using SNAPtide as substrate preincubated with enzyme for 0.5 to 30 mins followed by substrate addition by Michaelis-Menten equation analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
269.391.531.53
241.330.740.74
227.310.350.35
255.361.141.14