Basic Information
ID: ALA4670644
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsome using midazolam as substrate measured after 20 mins in presence of NADPH by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4670644
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 531.44 | 4.21 | 4.21 |
| 389.48 | 5.02 | 5.02 |
| 622.36 | 5.42 | 5.42 |
| 389.48 | 5.02 | 5.02 |