Basic Information
ID: ALA4670650
Type: Binding
Description: Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition by liquid scintillation counting method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: Solute carrier family 22 member 12(ALA6120)
Document: ALA4665798
Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition by liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670650
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.29 | 4.24 | 4.24 |
| 579.45 | 4.94 | 4.94 |
| 389.48 | 5.02 | 5.02 |
| 389.48 | 5.02 | 5.02 |
| 622.36 | 5.42 | 5.42 |
| 389.48 | 5.02 | 5.02 |