Basic Information
ID: ALA4670668
Type: Binding
Description: Potency index, ratio of EC50 for N/OFQ(1-13)-NH2 to EC50 for test compound for agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-arrestin2 activation incubated for 15 mins by BRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Nociceptin receptor(ALA2014)
Document: ALA4665800
Potency index, ratio of EC50 for N/OFQ(1-13)-NH2 to EC50 for test compound for agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-arrestin2 activation incubated for 15 mins by BRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670668
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1381.61 | ||
| 1347.59 | ||
| 1387.66 | ||
| 1381.61 | ||
| 1395.64 | ||
| 1471.73 | ||
| 1905.39 | ||
| 1351.58 | ||
| 2033.53 | ||
| 1395.64 | ||
| 1395.64 | ||
| 1384.68 | ||
| 2783.94 | ||
| 2832.10 | ||
| 1877.34 | ||
| 1394.61 | ||
| 2102.41 | ||
| 2699.77 | ||
| 1721.15 | ||
| 1324.51 | ||
| 1381.61 | ||
| 1379.64 | ||
| 1420.65 | ||
| 1381.61 | ||
| 1399.60 | ||
| 1381.61 | ||
| 1305.51 | ||
| 1381.61 | ||
| 1395.64 | ||
| 1393.62 | ||
| 1395.64 | ||
| 1381.61 | ||
| 1381.61 | ||
| 1305.51 | ||
| 1296.50 | ||
| 2778.30 | ||
| 1324.51 | ||
| 1790.26 | ||
| 2435.98 | ||
| 1421.67 | ||
| 1381.61 | ||
| 1395.64 | ||
| 1296.50 | ||
| 1365.61 | ||
| 2916.26 | ||
| 1749.17 | ||
| 1777.14 | ||
| 1395.64 | ||
| 1421.67 | ||
| 1381.61 | ||
| 2216.82 | ||
| 1806.26 | ||
| 2862.46 | ||
| 1849.29 |