Basic Information
ID: ALA4670708
Type: Binding
Description: Inhibition of LDHA in human MIA PaCa-2 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MIA PaCa-2
Target: L-lactate dehydrogenase A chain(ALA4835)
Document: ALA4665801
Inhibition of LDHA in human MIA PaCa-2 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670708
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 570.70 | 5.55 | 5.55 |
| 634.78 | 6.56 | 6.56 |
| 632.78 | 6.20 | 6.20 |
| 617.68 | 4.72 | 4.72 |
| 606.68 | 5.83 | 5.83 |
| 608.69 | 5.31 | 5.31 |
| 664.78 | 6.32 | 6.32 |
| 686.86 | 7.14 | 7.14 |
| 672.83 | 6.75 | 6.75 |
| 606.68 | 5.80 | 5.80 |
| 579.61 | 4.04 | 4.04 |
| 624.69 | 4.55 | 4.55 |
| 624.67 | 6.19 | 6.19 |
| 664.78 | 6.32 | 6.32 |
| 668.74 | 6.42 | 6.42 |
| 650.75 | 5.93 | 5.93 |
| 618.76 | 5.81 | 5.81 |
| 652.75 | 5.07 | 5.07 |
| 604.73 | 5.57 | 5.57 |
| 637.73 | 4.51 | 4.51 |
| 638.72 | 4.80 | 4.80 |
| 646.79 | 6.10 | 6.10 |
| 653.18 | 6.14 | 6.14 |
| 570.64 | 5.20 | 5.20 |
| 596.68 | 5.31 | 5.31 |
| 640.69 | 3.52 | 3.52 |
| 612.72 | 6.22 | 6.22 |
| 632.76 | 5.79 | 5.79 |
| 692.84 | 6.92 | 6.92 |
| 596.68 | 5.59 | 5.59 |
| 616.70 | 5.33 | 5.33 |
| 592.65 | 5.72 | 5.72 |
| 658.80 | 6.36 | 6.36 |
| 651.74 | 5.33 | 5.33 |
| 588.69 | 5.69 | 5.69 |
| 646.79 | 6.18 | 6.18 |
| 604.61 | 4.78 | 4.78 |
| 616.74 | 5.57 | 5.57 |
| 630.77 | 5.81 | 5.81 |
| 642.68 | 4.50 | 4.50 |
| 660.82 | 6.49 | 6.49 |
| 637.73 | 4.61 | 4.61 |
| 554.60 | 4.14 | 4.14 |
| 596.68 | 5.17 | 5.17 |
| 584.72 | 5.94 | 5.94 |
| 610.71 | 5.70 | 5.70 |
| 647.78 | 5.58 | 5.58 |
| 582.65 | 4.92 | 4.92 |
| 600.64 | 4.87 | 4.87 |
| 633.75 | 5.19 | 5.19 |
| 651.74 | 5.33 | 5.33 |
| 622.60 | 5.08 | 5.08 |
| 646.79 | 6.10 | 6.10 |
| 624.74 | 6.37 | 6.37 |
| 594.67 | 4.92 | 4.92 |
| 654.74 | 6.04 | 6.04 |
| 686.73 | 6.50 | 6.50 |
| 632.76 | 5.79 | 5.79 |
| 632.76 | 5.79 | 5.79 |
| 622.72 | 5.70 | 5.70 |
| 550.64 | 4.40 | 4.40 |
| 633.75 | 5.19 | 5.19 |
| 598.65 | 4.16 | 4.16 |
| 588.69 | 5.69 | 5.69 |
| 610.71 | 5.56 | 5.56 |
| 633.75 | 5.19 | 5.19 |
| 610.71 | 5.56 | 5.56 |
| 647.78 | 5.58 | 5.58 |
| 588.69 | 5.69 | 5.69 |
| 608.69 | 5.31 | 5.31 |
| 618.76 | 5.96 | 5.96 |
| 606.62 | 5.60 | 5.60 |
| 598.65 | 3.90 | 3.90 |
| 634.69 | 4.30 | 4.30 |
| 636.75 | 6.09 | 6.09 |
| 568.63 | 4.53 | 4.53 |
| 647.78 | 5.58 | 5.58 |
| 634.69 | 4.30 | 4.30 |
| 644.79 | 6.20 | 6.20 |
| 598.63 | 5.70 | 5.70 |
| 636.73 | 5.62 | 5.62 |
| 656.71 | 4.89 | 4.89 |
| 660.82 | 6.61 | 6.61 |
| 630.72 | 5.72 | 5.72 |
| 638.72 | 5.08 | 5.08 |
| 653.73 | 3.85 | 3.85 |
| 654.72 | 3.91 | 3.91 |
| 634.69 | 5.46 | 5.46 |
| 672.83 | 6.75 | 6.75 |