Basic Information
ID: ALA4670741
Type: Binding
Description: Inhibition of FITC-9mer Nrf2 peptide interaction with human recombinant Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli DE3 cells incubated for 30 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4670741
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 614.65 | 3.42 | 3.42 |
| 668.71 | 3.32 | 3.32 |
| 526.64 | 4.51 | 4.51 |
| 452.58 | 4.79 | 4.79 |
| 615.64 | 2.81 | 2.81 |
| 716.77 | 2.57 | 2.57 |
| 484.53 | 3.18 | 3.18 |
| 639.63 | 4.29 | 4.29 |
| 879.00 | 4.34 | 4.34 |
| 695.79 | 4.65 | 4.65 |
| 669.70 | 3.97 | 3.97 |
| 695.79 | 4.65 | 4.65 |
| 480.59 | 4.59 | 4.59 |
| 879.00 | 4.34 | 4.34 |
| 468.53 | 3.68 | 3.68 |
| 861.03 | 5.25 | 5.25 |
| 508.64 | 4.77 | 4.77 |
| 494.61 | 4.46 | 4.46 |
| 478.61 | 4.76 | 4.76 |
| 494.61 | 4.46 | 4.46 |
| 532.58 | 5.47 | 5.47 |
| 540.69 | 6.12 | 6.12 |
| 495.56 | 3.63 | 3.63 |
| 832.98 | 4.63 | 4.63 |
| 524.64 | 4.47 | 4.47 |
| 524.64 | 4.47 | 4.47 |
| 691.83 | 4.82 | 4.82 |
| 812.95 | 3.43 | 3.43 |
| 464.59 | 4.45 | 4.45 |
| 818.95 | 4.32 | 4.32 |
| 727.86 | 5.66 | 5.66 |
| 544.65 | 3.65 | 3.65 |
| 705.86 | 5.07 | 5.07 |
| 848.98 | 4.33 | 4.33 |
| 468.58 | 4.95 | 4.95 |
| 876.00 | 4.28 | 4.28 |
| 472.54 | 4.78 | 4.78 |
| 573.51 | 5.23 | 5.23 |
| 509.58 | 4.36 | 4.36 |
| 705.85 | 5.13 | 5.13 |
| 707.83 | 4.52 | 4.52 |
| 492.64 | 5.07 | 5.07 |
| 745.80 | 5.53 | 5.53 |
| 691.83 | 4.82 | 4.82 |
| 522.67 | 5.24 | 5.24 |
| 494.61 | 4.98 | 4.98 |
| 564.66 | 4.25 | 4.25 |
| 840.88 | 3.79 | 3.79 |
| 864.98 | 4.04 | 4.04 |
| 893.03 | 4.73 | 4.73 |
| 737.85 | 4.53 | 4.53 |
| 532.58 | 5.47 | 5.47 |
| 683.83 | 4.57 | 4.57 |
| 691.83 | 4.82 | 4.82 |
| 707.83 | 4.52 | 4.52 |
| 538.62 | 4.09 | 4.09 |
| 494.61 | 4.46 | 4.46 |
| 677.80 | 4.51 | 4.51 |
| 855.01 | 4.39 | 4.39 |
| 756.70 | 5.27 | 5.27 |
| 863.01 | 4.64 | 4.64 |
| 492.64 | 5.07 | 5.07 |
| 866.97 | 4.47 | 4.47 |
| 454.55 | 4.64 | 4.64 |
| 483.50 | 3.58 | 3.58 |
| 721.85 | 4.83 | 4.83 |
| 836.94 | 4.46 | 4.46 |
| 478.61 | 4.76 | 4.76 |
| 454.55 | 4.64 | 4.64 |
| 512.60 | 4.60 | 4.60 |
| 499.03 | 5.11 | 5.11 |
| 522.55 | 5.66 | 5.66 |
| 543.48 | 5.22 | 5.22 |
| 756.70 | 5.27 | 5.27 |
| 712.25 | 5.16 | 5.16 |
| 468.58 | 4.95 | 4.95 |
| 849.97 | 3.73 | 3.73 |
| 745.80 | 5.53 | 5.53 |
| 761.80 | 5.41 | 5.41 |
| 712.25 | 5.16 | 5.16 |
| 489.60 | 4.33 | 4.33 |
| 721.85 | 4.91 | 4.91 |
| 508.64 | 4.85 | 4.85 |
| 468.58 | 4.95 | 4.95 |
| 786.91 | 2.90 | 2.90 |
| 916.98 | 5.35 | 5.35 |
| 452.53 | 3.98 | 3.98 |
| 347.44 | 3.20 | 3.20 |
| 456.50 | 3.81 | 3.81 |
| 499.03 | 5.11 | 5.11 |
| 484.57 | 4.65 | 4.65 |
| 848.98 | 4.33 | 4.33 |
| 877.03 | 4.89 | 4.89 |
| 478.57 | 4.84 | 4.84 |
| 678.79 | 3.90 | 3.90 |
| 879.00 | 4.34 | 4.34 |
| 508.60 | 4.10 | 4.10 |
| 543.48 | 5.22 | 5.22 |
| 848.98 | 4.33 | 4.33 |
| 615.73 | 3.08 | 3.08 |
| 468.58 | 4.95 | 4.95 |
| 705.85 | 5.13 | 5.13 |