Basic Information
ID: ALA4670872
Type: Binding
Description: Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability
Format: BAO_0000219
Organism: Homo sapiens
Cell type: LOX IMVI
Target: Phospholipid hydroperoxide glutathione peroxidase(ALA4295754)
Document: ALA4665807
Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670872
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 359.81 | 3.75 | 3.75 |
| 477.41 | 5.08 | 5.08 |
| 281.83 | 4.54 | 4.54 |
| 475.33 | 4.75 | 4.75 |
| 391.30 | 3.82 | 3.82 |
| 199.17 | 0.59 | 0.59 |
| 557.84 | 5.83 | 5.83 |
| 375.30 | 4.41 | 4.41 |
| 460.79 | 5.59 | 5.59 |
| 440.88 | 3.21 | 3.21 |
| 460.79 | 5.59 | 5.59 |
| 521.86 | 5.24 | 5.24 |
| 587.22 | ||
| 504.80 | 6.10 | 6.10 |
| 539.85 | 5.53 | 5.53 |
| 563.40 | 6.31 | 6.31 |
| 511.25 | 5.11 | 5.11 |
| 397.73 | 4.47 | 4.47 |
| 440.88 | 3.21 | 3.21 |
| 433.34 | 3.96 | 3.96 |
| 437.41 | 4.03 | 4.03 |
| 414.34 | 4.70 | 4.70 |
| 525.15 | ||
| 359.43 | 4.82 | 4.82 |
| 497.22 | 4.72 | 4.72 |
| 326.31 | 2.57 | 2.57 |
| 420.30 | 4.02 | 4.02 |
| 445.47 | ||
| 454.98 | 5.03 | 5.03 |
| 530.99 | 4.30 | 4.30 |
| 373.28 | 3.86 | 3.86 |
| 518.48 | 3.49 | 3.49 |
| 567.23 | ||
| 518.48 | 3.49 | 3.49 |
| 609.31 | ||
| 511.04 | 4.62 | 4.62 |
| 209.16 | 0.25 | 0.25 |
| 466.99 | 4.87 | 4.87 |
| 389.33 | 4.80 | 4.80 |
| 501.99 | 4.51 | 4.51 |
| 555.01 | 5.36 | 5.36 |
| 452.96 | 4.48 | 4.48 |
| 488.35 | 5.59 | 5.59 |
| 387.31 | 4.25 | 4.25 |
| 506.34 | 5.73 | 5.73 |
| 495.40 | 5.38 | 5.38 |
| 513.39 | 5.67 | 5.67 |
| 248.71 | 2.29 | 2.29 |