Basic Information
ID: ALA4670874
Type: Binding
Description: Selectivity ratio of EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 to EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability
Format: BAO_0000219
Organism: Homo sapiens
Cell type: LOX IMVI
Target: Phospholipid hydroperoxide glutathione peroxidase(ALA4295754)
Document: ALA4665807
Selectivity ratio of EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 to EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4670874
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 477.41 | 5.08 | 5.08 |
| 475.33 | 4.75 | 4.75 |
| 440.88 | 3.21 | 3.21 |
| 521.86 | 5.24 | 5.24 |
| 587.22 | ||
| 397.73 | 4.47 | 4.47 |
| 433.34 | 3.96 | 3.96 |
| 414.34 | 4.70 | 4.70 |
| 525.15 | ||
| 420.30 | 4.02 | 4.02 |
| 445.47 | ||
| 373.28 | 3.86 | 3.86 |
| 567.23 | ||
| 511.04 | 4.62 | 4.62 |
| 452.96 | 4.48 | 4.48 |
| 387.31 | 4.25 | 4.25 |