Assay Report Card

Basic Information

ID: ALA4670893

Type: Binding

Description: Binding affinity to BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of Vgamma9/Vdelta2 T cell mediated T-24 cell lysis co-expressing GFP at 10 pM preincubated 4 hrs followed by compound washout and subsequent Vgamma9Vdelta2 T cell addition at 8:1 effector/target ratio and measured after 18 hrs by fluorescence based assay

Organism: Homo sapiens

Cell type: Vgamma9Vdelta2 T cell

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
262.090.150.15
453.424.904.90
383.433.913.91
417.444.314.31
419.414.504.50