Basic Information
ID: ALA4670927
Type: Binding
Description: Inhibiton of EGFR L858R/T790M mutant (unknown origin) expressed in human NCI-H1975 cells assessed as reduction in EGFR induced cell viability after 96 hrs by CellTiter-Glo assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4670927
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.07 | 6.14 | 6.14 |
| 557.05 | 5.93 | 5.93 |
| 485.95 | 4.39 | 4.39 |
| 499.62 | 4.51 | 4.51 |
| 545.60 | 5.26 | 5.26 |
| 584.08 | 6.06 | 6.06 |
| 496.96 | 6.12 | 6.12 |
| 514.55 | 5.29 | 5.29 |