Basic Information
ID: ALA4670929
Type: Binding
Description: Inhibition of human N-terminal GST-tagged EGFR L858R/T790M mutant (669 to 1210 residues) expressed in baculovirus infected Sf9 insect cells using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4670929
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.07 | 6.14 | 6.14 |
| 557.05 | 5.93 | 5.93 |
| 485.95 | 4.39 | 4.39 |
| 499.62 | 4.51 | 4.51 |
| 545.60 | 5.26 | 5.26 |
| 584.08 | 6.06 | 6.06 |
| 496.96 | 6.12 | 6.12 |
| 514.55 | 5.29 | 5.29 |