Basic Information
ID: ALA4670944
Type: Binding
Description: Inhibition of HER2-A775_G776insYVMA mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in HER2 induced cell viability after 96 hrs by CellTiter-Glo assay
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4670944
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.07 | 6.14 | 6.14 |
| 446.91 | 4.28 | 4.28 |
| 557.05 | 5.93 | 5.93 |
| 485.95 | 4.39 | 4.39 |
| 547.97 | 5.92 | 5.92 |
| 499.62 | 4.51 | 4.51 |
| 491.35 | 5.38 | 5.38 |
| 688.79 | 6.71 | 6.71 |
| 513.96 | 6.86 | 6.86 |
| 510.64 | 4.59 | 4.59 |
| 482.59 | 4.57 | 4.57 |
| 537.62 | 7.66 | 7.66 |
| 711.87 | 9.08 | 9.08 |
| 794.92 | 8.21 | 8.21 |
| 585.06 | 6.53 | 6.53 |
| 601.67 | 5.23 | 5.23 |
| 510.64 | 5.20 | 5.20 |
| 793.93 | 8.25 | 8.25 |
| 485.55 | 5.96 | 5.96 |
| 545.60 | 5.26 | 5.26 |
| 584.08 | 6.06 | 6.06 |
| 671.21 | 7.54 | 7.54 |
| 545.65 | 5.62 | 5.62 |
| 484.56 | 6.50 | 6.50 |
| 447.50 | 6.29 | 6.29 |
| 496.62 | 4.52 | 4.52 |
| 571.04 | 5.88 | 5.88 |
| 545.60 | 5.33 | 5.33 |
| 445.53 | 6.08 | 6.08 |
| 468.56 | 4.18 | 4.18 |
| 485.55 | 5.89 | 5.89 |
| 530.54 | 5.13 | 5.13 |
| 574.60 | 4.66 | 4.66 |
| 468.56 | 3.47 | 3.47 |
| 557.01 | 5.49 | 5.49 |
| 496.96 | 6.12 | 6.12 |
| 688.21 | 8.28 | 8.28 |
| 514.55 | 5.29 | 5.29 |
| 482.59 | 3.95 | 3.95 |
| 496.62 | 4.96 | 4.96 |
| 704.79 | 6.54 | 6.54 |