Basic Information
ID: ALA4670946
Type: Binding
Description: Inhibition of C-terminal His6-tagged HER2-A775_G776insYVMA mutant (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 40 mins in presence of XL665-labeled streptavidin by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4670946
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.07 | 6.14 | 6.14 |
| 446.91 | 4.28 | 4.28 |
| 557.05 | 5.93 | 5.93 |
| 485.95 | 4.39 | 4.39 |
| 547.97 | 5.92 | 5.92 |
| 499.62 | 4.51 | 4.51 |
| 491.35 | 5.38 | 5.38 |
| 688.79 | 6.71 | 6.71 |
| 513.96 | 6.86 | 6.86 |
| 510.64 | 4.59 | 4.59 |
| 482.59 | 4.57 | 4.57 |
| 537.62 | 7.66 | 7.66 |
| 711.87 | 9.08 | 9.08 |
| 794.92 | 8.21 | 8.21 |
| 585.06 | 6.53 | 6.53 |
| 601.67 | 5.23 | 5.23 |
| 510.64 | 5.20 | 5.20 |
| 793.93 | 8.25 | 8.25 |
| 485.55 | 5.96 | 5.96 |
| 545.60 | 5.26 | 5.26 |
| 584.08 | 6.06 | 6.06 |
| 671.21 | 7.54 | 7.54 |
| 545.65 | 5.62 | 5.62 |
| 484.56 | 6.50 | 6.50 |
| 447.50 | 6.29 | 6.29 |
| 496.62 | 4.52 | 4.52 |
| 571.04 | 5.88 | 5.88 |
| 545.60 | 5.33 | 5.33 |
| 445.53 | 6.08 | 6.08 |
| 468.56 | 4.18 | 4.18 |
| 485.55 | 5.89 | 5.89 |
| 530.54 | 5.13 | 5.13 |
| 574.60 | 4.66 | 4.66 |
| 468.56 | 3.47 | 3.47 |
| 557.01 | 5.49 | 5.49 |
| 496.96 | 6.12 | 6.12 |
| 688.21 | 8.28 | 8.28 |
| 514.55 | 5.29 | 5.29 |
| 482.59 | 3.95 | 3.95 |
| 496.62 | 4.96 | 4.96 |
| 704.79 | 6.54 | 6.54 |