Basic Information
ID: ALA4670995
Type: Binding
Description: Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effector Jurkat T cells at 0.01 to 100 uM incubated for 6 hrs by luciferase reporter gene based immune checkpoint blockade cell-based assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4670995
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 617.33 | 6.67 | 6.67 |
| 453.38 | 4.92 | 4.92 |
| 401.51 | 5.37 | 5.37 |
| 532.82 | 7.61 | 7.61 |
| 533.81 | 7.01 | 7.01 |
| 531.01 | 7.91 | 7.91 |
| 431.53 | 5.38 | 5.38 |
| 480.40 | 6.13 | 6.13 |
| 648.94 | 6.21 | 6.21 |
| 415.53 | 5.68 | 5.68 |