Basic Information
ID: ALA4670999
Type: Binding
Description: Binding affinity to human PD1 (34-150 residues) extracellular domain C93S mutant expressed in Escherichia coli BL21 (DE3) incubated for 2 hrs by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4670999
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 557.29 | 5.55 | 5.55 |
| 545.91 | 5.15 | 5.15 |
| 617.33 | 6.67 | 6.67 |
| 453.38 | 4.92 | 4.92 |
| 401.51 | 5.37 | 5.37 |
| 529.41 | 4.83 | 4.83 |
| 397.27 | 5.52 | 5.52 |
| 532.82 | 7.61 | 7.61 |
| 202.23 | 2.99 | 2.99 |
| 577.29 | 7.04 | 7.04 |
| 387.25 | 5.33 | 5.33 |
| 533.81 | 7.01 | 7.01 |
| 384.07 | 4.78 | 4.78 |
| 531.01 | 7.91 | 7.91 |
| 367.24 | 5.51 | 5.51 |
| 443.27 | 5.42 | 5.42 |
| 446.14 | 6.27 | 6.27 |
| 344.02 | 5.15 | 5.15 |
| 443.34 | 7.17 | 7.17 |
| 260.26 | 2.76 | 2.76 |
| 464.13 | 6.41 | 6.41 |
| 431.53 | 5.38 | 5.38 |
| 558.47 | 6.38 | 6.38 |
| 480.40 | 6.13 | 6.13 |
| 583.32 | 5.83 | 5.83 |
| 504.42 | 5.06 | 5.06 |
| 550.27 | 5.82 | 5.82 |
| 414.89 | 6.77 | 6.77 |
| 476.16 | 6.24 | 6.24 |
| 648.94 | 6.21 | 6.21 |
| 381.27 | 5.82 | 5.82 |
| 471.15 | 6.14 | 6.14 |
| 417.69 | 5.87 | 5.87 |
| 415.53 | 5.68 | 5.68 |
| 260.34 | 4.51 | 4.51 |
| 351.04 | 4.88 | 4.88 |
| 326.03 | 5.01 | 5.01 |
| 504.17 | 6.04 | 6.04 |