Assay Report Card

Basic Information

ID: ALA4671076

Type: Binding

Description: Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux incubated for 140 sec by FluoZin2-AM dye based fluorescence analysis relative to maximal induction of L-AP4

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
418.473.743.74
417.493.413.41
408.454.504.50
362.413.583.58
383.423.723.72