Assay Report Card

Basic Information

ID: ALA4671293

Type: Binding

Description: Inhibition of RANKL (unknown origin) in RANKL cultured mouse RAW264.7 cells assessed as reduction in RANKL/RANK-interaction mediated NFATc1 expression by measuring NFATc1 protein expression at 2 uM preincubated for 1 hr followed by cell culture addition and measured after 2 days by Western blot analysis relative to positive control (Rvb = 1 No_unit)

Organism: Homo sapiens

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
524.534.494.49
554.612.932.93