Basic Information
ID: ALA4671298
Type: Binding
Description: Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in phalloidin-labeled actin ring formation at 5 to 10 uM preincubated with RANKL for 1 hr followed by cell addition and subsequent media replenishment every 48 hrs for 4 days by Alexa Fluor 488-conjugated phalloidin/DAPI-staining based fluorescence microscopic analysis
Organism: Homo sapiens
Cell type: Bone marrow cell
Activity Charts
Bioactivity
Activity Types for Assay ALA4671298
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 515.64 | 4.55 | 4.55 |