Basic Information
ID: ALA4671306
Type: Binding
Description: Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP activity preincubated with RANKL for 1 hr followed by cell addition and subsequent media replenishment every 48 hrs for 4 days
Organism: Homo sapiens
Cell type: Bone marrow cell
Activity Charts
Bioactivity
Activity Types for Assay ALA4671306
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.62 | 6.94 | 6.94 |
| 524.53 | 4.49 | 4.49 |
| 543.60 | 3.83 | 3.83 |
| 588.60 | 3.74 | 3.74 |
| 599.60 | 2.84 | 2.84 |
| 556.62 | 3.18 | 3.18 |
| 581.63 | 3.05 | 3.05 |
| 579.62 | 2.80 | 2.80 |
| 515.64 | 4.55 | 4.55 |
| 554.61 | 2.93 | 2.93 |
| 601.62 | 3.09 | 3.09 |