ID: ALA4671528
Type: Functional
Description: Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins followed by PGF2alpha stimulation and measured for 120 secs by fluo-8 AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: Chem-1
Bioactivity
Activity Types for Assay ALA4671528
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
544.88 | 5.94 | 5.94 |
495.30 | 5.30 | 5.30 |
566.83 | 5.79 | 5.79 |
523.81 | 6.22 | 6.22 |
551.87 | 7.00 | 7.00 |
537.84 | 6.61 | 6.61 |
499.72 | 6.41 | 6.41 |
446.35 | 5.34 | 5.34 |
587.85 | 7.28 | 7.28 |
594.88 | 6.61 | 6.61 |
503.34 | 5.54 | 5.54 |
526.31 | 5.90 | 5.90 |
544.88 | 5.94 | 5.94 |
434.85 | 5.95 | 5.95 |
586.96 | 6.96 | 6.96 |
460.38 | 5.68 | 5.68 |
565.90 | 7.39 | 7.39 |
460.38 | 5.90 | 5.90 |
479.31 | 6.06 | 6.06 |
456.52 | 6.60 | 6.60 |
465.32 | 6.42 | 6.42 |
495.30 | 5.15 | 5.15 |
505.34 | 6.63 | 6.63 |
533.42 | 5.97 | 5.97 |
489.41 | 6.51 | 6.51 |
533.42 | 5.97 | 5.97 |
461.32 | 5.92 | 5.92 |
533.42 | 5.97 | 5.97 |
446.35 | 5.34 | 5.34 |
558.90 | 6.33 | 6.33 |
460.38 | 5.73 | 5.73 |
468.41 | 6.32 | 6.32 |
572.93 | 6.72 | 6.72 |
478.32 | 5.46 | 5.46 |
493.40 | 5.88 | 5.88 |
478.32 | 6.67 | 6.67 |
452.38 | 5.40 | 5.40 |
466.31 | 6.39 | 6.39 |