Basic Information
ID: ALA4671765
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericin
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA4665838
Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericin: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4671765
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.50 | 3.24 | 3.24 |