Basic Information
ID: ALA4671767
Type: Binding
Description: Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta production
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA4665838
Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta production: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4671767
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.49 | 2.99 | 2.99 |
| 447.58 | 3.47 | 3.47 |
| 383.47 | 3.18 | 3.18 |
| 463.65 | 4.50 | 4.50 |
| 369.42 | 2.28 | 2.28 |
| 377.37 | 3.28 | 3.28 |
| 403.53 | 3.55 | 3.55 |
| 389.50 | 3.24 | 3.24 |
| 393.53 | 4.51 | 4.51 |
| 419.53 | 2.74 | 2.74 |
| 393.45 | 2.14 | 2.14 |
| 389.50 | 3.24 | 3.24 |
| 388.51 | 3.85 | 3.85 |
| 460.58 | 2.94 | 2.94 |
| 388.51 | 3.85 | 3.85 |
| 403.53 | 3.55 | 3.55 |
| 403.53 | 3.55 | 3.55 |
| 439.56 | 4.40 | 4.40 |
| 445.37 | 4.30 | 4.30 |
| 479.65 | 3.51 | 3.51 |
| 383.47 | 3.18 | 3.18 |
| 365.48 | 3.50 | 3.50 |
| 495.65 | 3.18 | 3.18 |
| 430.53 | 3.61 | 3.61 |
| 389.50 | 3.24 | 3.24 |
| 395.36 | 3.42 | 3.42 |