Basic Information
ID: ALA4671932
Type: Binding
Description: Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Organism: Homo sapiens
Cell type: HeLa
Subcellular Fraction: Nucleus
Activity Charts
Bioactivity
Activity Types for Assay ALA4671932
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 616.73 | 4.67 | 4.67 |
| 489.54 | 3.60 | 3.60 |
| 589.70 | 5.32 | 5.32 |
| 575.68 | 4.93 | 4.93 |
| 547.62 | 4.15 | 4.15 |
| 621.70 | 5.58 | 5.58 |
| 474.53 | 4.18 | 4.18 |
| 588.68 | 3.89 | 3.89 |
| 595.67 | 5.18 | 5.18 |
| 602.70 | 4.28 | 4.28 |
| 603.73 | 5.71 | 5.71 |
| 430.52 | 4.49 | 4.49 |
| 648.73 | 4.93 | 4.93 |
| 622.69 | 4.53 | 4.53 |
| 561.65 | 4.54 | 4.54 |