Basic Information
ID: ALA4672177
Type: Functional
Description: Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 60 mins by Hit-hunter assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4665860
Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 60 mins by Hit-hunter assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4672177
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.40 | 5.24 | 5.24 |
| 362.45 | 5.61 | 5.61 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 427.50 | 5.08 | 5.08 |
| 346.39 | 3.98 | 3.98 |
| 398.51 | 6.54 | 6.54 |
| 376.84 | 5.90 | 5.90 |
| 356.43 | 5.44 | 5.44 |
| 376.84 | 5.90 | 5.90 |
| 347.37 | 4.54 | 4.54 |
| 331.38 | 4.57 | 4.57 |
| 411.29 | 6.55 | 6.55 |
| 356.43 | 5.55 | 5.55 |
| 411.51 | 5.84 | 5.84 |
| 356.43 | 5.55 | 5.55 |
| 411.51 | 5.84 | 5.84 |
| 410.40 | 6.26 | 6.26 |
| 418.50 | 6.91 | 6.91 |
| 346.39 | 3.98 | 3.98 |
| 349.42 | 4.70 | 4.70 |
| 376.84 | 5.90 | 5.90 |
| 425.53 | 6.23 | 6.23 |
| 332.36 | 4.84 | 4.84 |
| 411.51 | 5.84 | 5.84 |
| 392.46 | 6.40 | 6.40 |
| 372.42 | 5.25 | 5.25 |
| 372.42 | 5.25 | 5.25 |
| 333.35 | 4.23 | 4.23 |
| 410.40 | 6.26 | 6.26 |
| 363.44 | 5.01 | 5.01 |
| 348.45 | 5.78 | 5.78 |
| 356.43 | 5.55 | 5.55 |
| 348.43 | 5.31 | 5.31 |
| 348.43 | 5.31 | 5.31 |
| 372.42 | 5.25 | 5.25 |
| 410.39 | 6.26 | 6.26 |
| 332.36 | 4.84 | 4.84 |
| 392.46 | 6.40 | 6.40 |
| 346.39 | 3.98 | 3.98 |