Basic Information
ID: ALA4672558
Type: Toxicity
Description: Therapeutic index, ratio of average IC50 for human MRC5 and BJ cells to IC50 for antileishmanial activity against Leishmania major
Format: BAO_0000019
Target: ADMET(ALA612558)
Document: ALA4665886
Therapeutic index, ratio of average IC50 for human MRC5 and BJ cells to IC50 for antileishmanial activity against Leishmania major: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4672558
TI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 924.09 | 0.71 | 0.71 |
| 407.58 | 5.68 | 5.68 |
| 395.46 | 3.92 | 3.92 |
| 396.90 | 4.82 | 4.82 |
| 452.54 | 5.03 | 5.03 |
| 449.49 | 5.13 | 5.13 |
| 368.85 | 4.04 | 4.04 |
| 441.35 | 4.93 | 4.93 |
| 457.35 | 3.90 | 3.90 |
| 500.63 | 3.61 | 3.61 |
| 470.53 | 5.17 | 5.17 |
| 420.49 | 3.71 | 3.71 |
| 427.33 | 4.54 | 4.54 |
| 301.40 | 3.55 | 3.55 |
| 412.90 | 3.79 | 3.79 |
| 407.46 | 4.07 | 4.07 |
| 362.46 | 4.17 | 4.17 |
| 334.40 | 3.39 | 3.39 |
| 348.43 | 3.78 | 3.78 |
| 438.94 | 5.88 | 5.88 |
| 578.57 | 6.33 | 6.33 |
| 402.59 | 4.95 | 4.95 |
| 526.54 | 5.83 | 5.83 |
| 448.94 | 5.55 | 5.55 |
| 481.67 | 3.60 | 3.60 |
| 470.58 | 5.97 | 5.97 |
| 441.57 | 5.09 | 5.09 |
| 322.50 | 4.23 | 4.23 |
| 419.55 | 3.43 | 3.43 |
| 302.31 | 2.74 | 2.74 |
| 470.58 | 5.97 | 5.97 |