Basic Information
ID: ALA4672634
Type: Binding
Description: Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation counting method
Organism: Rattus norvegicus
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4672634
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.38 | 2.89 | 2.89 |
| 381.51 | 3.39 | 3.39 |
| 381.44 | 2.09 | 2.09 |
| 367.41 | 2.16 | 2.16 |
| 410.50 | 2.11 | 2.11 |
| 365.50 | 4.52 | 4.52 |
| 271.32 | 1.24 | 1.24 |
| 397.50 | 3.09 | 3.09 |
| 416.50 | 4.63 | 4.63 |
| 417.49 | 4.02 | 4.02 |
| 395.53 | 3.70 | 3.70 |
| 424.49 | 1.91 | 1.91 |
| 337.38 | 2.15 | 2.15 |
| 382.49 | 2.19 | 2.19 |
| 383.40 | 4.19 | 4.19 |
| 337.38 | 2.15 | 2.15 |
| 392.49 | 2.96 | 2.96 |
| 367.48 | 3.08 | 3.08 |
| 381.51 | 3.47 | 3.47 |
| 337.38 | 2.15 | 2.15 |
| 380.52 | 4.00 | 4.00 |
| 409.56 | 4.21 | 4.21 |
| 403.43 | 3.46 | 3.46 |
| 307.36 | 2.14 | 2.14 |
| 449.50 | 4.41 | 4.41 |
| 388.43 | 2.76 | 2.76 |
| 372.42 | 3.45 | 3.45 |
| 368.47 | 1.85 | 1.85 |
| 424.49 | 1.91 | 1.91 |
| 424.49 | 1.91 | 1.91 |
| 313.41 | 2.41 | 2.41 |
| 435.48 | 4.10 | 4.10 |
| 332.37 | 2.02 | 2.02 |
| 365.39 | 1.92 | 1.92 |
| 369.45 | 2.28 | 2.28 |
| 392.84 | 3.80 | 3.80 |
| 375.35 | 3.16 | 3.16 |
| 397.44 | 2.17 | 2.17 |