Basic Information
ID: ALA4672683
Type: ADME
Description: Activation of human PXR human hepatocytes assessed as induction of CYP3A4 mRNA expression incubated for 48 hrs by qPCR analysis
Organism: Homo sapiens
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4672683
NOAEL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 627.75 | 5.81 | 5.81 |
| 505.97 | 4.61 | 4.61 |
| 473.96 | 4.28 | 4.28 |
| 502.01 | 5.06 | 5.06 |
| 460.92 | 3.11 | 3.11 |
| 459.93 | 3.88 | 3.88 |
| 491.95 | 4.22 | 4.22 |
| 473.96 | 3.01 | 3.01 |
| 429.90 | 3.94 | 3.94 |
| 474.95 | 3.50 | 3.50 |