Assay Report Card

Basic Information

ID: ALA4673569

Type: Binding

Description: Inhibition of Cx43 in hypoxic-acidic ion-shifted ringers solution-induced human cerebral microvascular endothelial cell model of ischaemic injury assessed as ATP release at 10 uM measured after 2 hrs by luciferin-luciferase based luminescence assay relative to control

Organism: Homo sapiens

Cell type: Cerebral microvascular endothelial cell

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
570.776.836.83
1603.88
1567.94
1395.60
1595.95
1680.16
1634.04
1597.92
1682.08
1597.88
1525.81
1527.79
1682.04
1609.98
1465.72
1525.81
1601.91
1511.79
1525.82
1539.84
1652.10
1483.78
1549.88
1511.79
1708.17
1722.19
1615.94
1611.90
1766.20
1595.95
1680.11
1555.84
1573.90
1710.14
1513.76
1708.17
1794.26
1662.09
1694.14
1680.11
1601.91
1479.74
1497.80
1688.00