Basic Information
ID: ALA4673773
Type: Binding
Description: Zinc chelating activity mediated inhibition of Clostridium botulinum Hall A hyper BoNT/A1activity assessed as inhibition of BoNT/A1-induced neurotoxicity in hIPSC derived GABA neurons by measuring protection against SNAP-25 cleavage incubated for 30 mins post BoNT/A1 addition and measured at 7 hrs post-toxin addition by Western blot analysis
Organism: Clostridium botulinum
Strain: Hall A hyper
Activity Charts
Bioactivity
Activity Types for Assay ALA4673773
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.40 | 5.23 | 5.23 |
| 351.43 | 4.68 | 4.68 |
| 325.41 | 5.09 | 5.09 |
| 341.86 | 5.60 | 5.60 |
| 314.24 | 4.78 | 4.78 |
| 276.32 | 3.19 | 3.19 |
| 321.44 | 5.14 | 5.14 |